Antenatal obstetric complications
- ‘Minor’ problems of pregnancy
- Backache – ue to laxity if spinal ligaments and exaggerated lumbar lordosis
- Symphysis pubis dysfunction
- Constipation – due to progesterone slowing gut motility
- Hyperemesis gravidarm
- Heartburn
- Varicose veins and piles – relaxant effect of progesterone on smooth muscle and the venous stasis caused by the weight of the pregnant uterus on the inferior vena cava
- Carpal tunnel
- Oedema
Problems due to abnormalities of pelvic organs
Fibroids
- If a large fibroid is at the uterus or lower segment it can prevent descent and obstruct delivery as well as causing Caesarean section complications
- Most common problem is red degeneration resulting in acute pain, tenderness and vomiting
- If symptoms are severe they can precipitate uterine contractions
Retroversion of the Uterus
- 15% of women have a retroverted uterus
- Most become anteverted during pregnancy
- If it fails to antevert can fill pelvis squashing the bladder and ureters. This can cause urinary retention and bladder over-distension
Congenital Uterine Anomalies
- Problems associated with a bicornuate uterus are;
- Miscarriage
- Pre-term labour
- PPROM
- Abnormal lie and presentation
- High Caesarean section rate
Urinary Tract Infections
- Common in pregnancy
- May progress to pyelonephritis
- Predisposing factors
- Hx of recurrent cystitis
- Renal tract abnormalities
- Bladder emptying problems e.g. MS
- Presenting symptoms – low back pain, malaise and flu-like symptoms
- First line treatment is amoxicillin or oral cephalosporins
Venous thromboembolism
- In pregnancy there is an increase in clotting factors VIII, IX, X and fibrinogen levels and a decreased in Protein S and anti-thrombin III levels
- Due to high levels of oestrogen
- Venous stasis also increases risk
- Pregnancy increases risk of DVT by 5 times
- Caesarean section increases risk of DVT by 10 times
- Specific risk factors associated with pregnancy;
- Multiple gestation
- Pre-eclampsia
- Multiparity
- Caesarean section
- Sepsis
- Prolonged bed rest
Thrombophilia
- Predisposition to thrombosis can be inherited or acquired
- Inherited conditions include, deficiencies in Protein C, Protein S and anti-thrombin III as well as resistance to activated protein C caused by Leiden mutation of Factor V
- Acquired thrombophilia is most commonly associated with anti-phospholipid syndrome which is a combination of lupus anticoagulants with or without anti-cardiolipin antibodies
- Individual should be considered for prophylaxis
DVT/PE
- D-Dimer can be elevated in pregnancy due to physiological changes in the coagulation system making it less useful for diagnosis
- Heparin – prolongs activated partial thromboplastin time (APPT) and is safe during pregnancy as it doesn’t cross the placenta
- Warfarin prolongs prothrombin time and crosses the placenta causing limb and facial defects in the first trimester and intracerebral haemorrhage in the second trimester
Antepartum Haemorrhage
- Defined as vaginal bleeding from 24 weeks up to delivery of the baby
- Placental causes include;
- Placental abruption
- Placenta praevia
- Vasa praevia
- Placental abruption
- Local causes include;
- Cervicitis
- Cervical ectropion
- Cervical carcinoma
- Vaginal trauma
- Vaginal infection
- Cervicitis
- Rhesus status is important, if women is rhesus negative give anti-D
Oligohydramnios/Polyhydramnios
- Amniotic fluid is produced almost exclusively from fetal urine from the second trimester onwards
- Protects baby from trauma
- Allows limb movement and development
- Allows fetal breathing – aiding lung development
Oligohydramnios
- Amniotic fluid index less than the 5th centile for gestation
- Diagnosed by amniotic fluid index (AFI), an ultrasound measurement
- May be due to PPROM whereby it leaks from the vagina or conditions where there is insufficient production such as;
- Renal agenesis
- Multicystic kidneys
- Urinary tract obstruction/abnormality
- IUGR/ placental insufficiency
- Maternal drugs – NSAIDs
- Altogether may cause fetal lung problems
Polyhydramnios
- AFI >95% centile for gestation
- Produces severe abdominal discomfort
- May be caused be maternal, placental or fetal conditions
- Maternal;
- Diabetes
- Diabetes
- Placental;
- Chorioangioma
- Arterio-venous fistula
- Chorioangioma
- Fetal;
- Multiple gestation
- Idiopathic
- Oesophageal/duodenal atresia
- Neuromuscular condition that prevent sswallowing
- Anecephaly
- Multiple gestation
- Risk of preterm labour due to overdistension
- Risk of abnormal lie and malpresentation
- To reduce liquor can use amniodrainage or NSAIDs to reduce fetal urine output
Breech presentation, oblique and transverse lie at term
- Breech is common before term and only becomes a problem if the baby is not cephalic by 37 weeks
- Three types are breech;
- Extended (frank) breech
- Flexed (complete) breech
- Footing breech
- Extended (frank) breech
- Cord and foot prolapse are risks
- Predisposing factors for abnormal lie or breech are
- Uterine;
- Fibroids
- Congenital deformities
- Uterine surgery
- Polyhydramnios
- Oligohydramnios
- Fibroids
- Fetal;
- Multiple gestation
- Abnormality e.g. anencephaly or hydrocephalus
- Neuromuscular condition
- Multiple gestation
- Particular problem if women is multiparous where the uterus is lax
- Elective Caesarean section is safer then vaginal delivery is baby is breech at term
External cephalic version
- May be performed at 36-37 weeks
- Contraindications
- Placenta praevia
- Oligohydramnios/polyhdramnios
- Hx of antepartum haemorrhage
- Previous uterine scar
- Multiple gestation
- Pre-eclampsia or hypertension
- Placenta praevia
- Risks of ECV
- Placental abrution
- Premature rupture of membranes
- Cord accident
- Transplacental haemorrhage
- Fetal bradycardia
- Placental abrution