Antenatal obstetric complications

  • ‘Minor’ problems of pregnancy
  • Backache – ue to laxity if spinal ligaments and exaggerated lumbar lordosis
  • Symphysis pubis dysfunction
  • Constipation – due to progesterone slowing gut motility
  • Hyperemesis gravidarm
  • Heartburn
  • Varicose veins and piles – relaxant effect of progesterone on smooth muscle and the venous stasis caused by the weight of the pregnant uterus on the inferior vena cava
  • Carpal tunnel
  • Oedema

 

Problems due to abnormalities of pelvic organs

 

Fibroids

  • If a large fibroid is at the uterus or lower segment it can prevent descent and obstruct delivery as well as causing Caesarean section complications
  • Most common problem is red degeneration resulting in acute pain, tenderness and vomiting
  • If symptoms are severe they can precipitate uterine contractions

 

Retroversion of the Uterus

  • 15% of women have a retroverted uterus
  • Most become anteverted during pregnancy
  • If it fails to antevert can fill pelvis squashing the bladder and ureters. This can cause urinary retention and bladder over-distension

 

Congenital Uterine Anomalies

  • Problems associated with a bicornuate uterus are;
  • Miscarriage
  • Pre-term labour
  • PPROM
  • Abnormal lie and presentation
  • High Caesarean section rate

 

Urinary Tract Infections

 

  • Common in pregnancy
  • May progress to pyelonephritis
  • Predisposing factors
  • Hx of recurrent cystitis
  • Renal tract abnormalities
  • Bladder emptying problems e.g. MS
  • Presenting symptoms – low back pain, malaise and flu-like symptoms
  • First line treatment is amoxicillin or oral cephalosporins

 

Venous thromboembolism

 

  • In pregnancy there is an increase in clotting factors VIII, IX, X and fibrinogen levels and a decreased in Protein S and anti-thrombin III levels
  • Due to high levels of oestrogen
  • Venous stasis also increases risk
  • Pregnancy increases risk of DVT by 5 times
  • Caesarean section increases risk of DVT by 10 times
  • Specific risk factors associated with pregnancy;
  • Multiple gestation
  • Pre-eclampsia
  • Multiparity
  • Caesarean section
  • Sepsis
  • Prolonged bed rest

 

Thrombophilia

  • Predisposition to thrombosis can be inherited or acquired
  • Inherited conditions include, deficiencies in Protein C, Protein S and anti-thrombin III as well as resistance to activated protein C caused by Leiden mutation of Factor V
  • Acquired thrombophilia is most commonly associated with anti-phospholipid syndrome which is a combination of lupus anticoagulants with or without anti-cardiolipin antibodies
  • Individual should be considered for prophylaxis

 

DVT/PE

  • D-Dimer can be elevated in pregnancy due to physiological changes in the coagulation system making it less useful for diagnosis
  • Heparin – prolongs activated partial thromboplastin time (APPT) and is safe during pregnancy as it doesn’t cross the placenta
  • Warfarin prolongs prothrombin time and crosses the placenta causing limb and facial defects in the first trimester and intracerebral haemorrhage in the second trimester

 

Antepartum Haemorrhage

 

  • Defined as vaginal bleeding from 24 weeks up to delivery of the baby
  • Placental causes include;
    • Placental abruption
    • Placenta praevia
    • Vasa praevia
  • Local causes include;
    • Cervicitis
    • Cervical ectropion
    • Cervical carcinoma
    • Vaginal trauma
    • Vaginal infection
  • Rhesus status is important, if women is rhesus negative give anti-D

 

Oligohydramnios/Polyhydramnios

 

  • Amniotic fluid is produced almost exclusively from fetal urine from the second trimester onwards
  • Protects baby from trauma
  • Allows limb movement and development
  • Allows fetal breathing – aiding lung development

 

Oligohydramnios

  • Amniotic fluid index less than the 5th centile for gestation
  • Diagnosed by amniotic fluid index (AFI), an ultrasound measurement
  • May be due to PPROM whereby it leaks from the vagina or conditions where there is insufficient production such as;
  • Renal agenesis
  • Multicystic kidneys
  • Urinary tract obstruction/abnormality
  • IUGR/ placental insufficiency
  • Maternal drugs – NSAIDs
  • Altogether may cause fetal lung problems

 

Polyhydramnios

  • AFI >95% centile for gestation
  • Produces severe abdominal discomfort
  • May be caused be maternal, placental or fetal conditions
  • Maternal;
    • Diabetes
  • Placental;
    • Chorioangioma
    • Arterio-venous fistula
  • Fetal;
    • Multiple gestation
    • Idiopathic
    • Oesophageal/duodenal atresia
    • Neuromuscular condition that prevent sswallowing
    • Anecephaly
  • Risk of preterm labour due to overdistension
  • Risk of abnormal lie and malpresentation
  • To reduce liquor can use amniodrainage or NSAIDs to reduce fetal urine output

 

 

Breech presentation, oblique and transverse lie at term

 

  • Breech is common before term and only becomes a problem if the baby is not cephalic by 37 weeks
  • Three types are breech;
    • Extended (frank) breech
    • Flexed (complete) breech
    • Footing breech
  • Cord and foot prolapse are risks
  • Predisposing factors for abnormal lie or breech are
  • Uterine;
    • Fibroids
    • Congenital deformities
    • Uterine surgery
    • Polyhydramnios
    • Oligohydramnios
  • Fetal;
    • Multiple gestation
    • Abnormality e.g. anencephaly or hydrocephalus
    • Neuromuscular condition
  • Particular problem if women is multiparous where the uterus is lax
  • Elective Caesarean section is safer then vaginal delivery is baby is breech at term

 

External cephalic version

  • May be performed at 36-37 weeks
  • Contraindications
    • Placenta praevia
    • Oligohydramnios/polyhdramnios
    • Hx of antepartum haemorrhage
    • Previous uterine scar
    • Multiple gestation
    • Pre-eclampsia or hypertension
  • Risks of ECV
    • Placental abrution
    • Premature rupture of membranes
    • Cord accident
    • Transplacental haemorrhage
    • Fetal bradycardia

 

 

 

 

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Disclaimer: These notes are my own personal study aid - DO NOT use them for medical advice!