Complications of Late Pregnancy

See obstetric emergencies

  • Placental abruption
  • Placenta praevia
  • Vasa praevia
  • Pre-eclampsia

Premature labour

  • Birth between 24 and 37 weeks (earlier births are referred to as miscarriages)
  • Complicates 7% of UK pregnancies
  • Babies born before 32 weeks account for more than half of all perinatal mortality
  • Half the survivors at 23-25 weeks will have some degree of functional impairment
  • Should be divided into,
    • Mildly preterm – 32-36 weeks
    • Very preterm – 28-32 weeks
    • Extremely preterm – 24-28 weeks

Aetiology

  • Infection e.g. bacterial vaginosis, UTI
  • Over-distention – multiple pregnancy and polyhydramnios
  • Vascular – antepartum haemorrhage, blood irritates myometrium and weakens membranes
  • Intercurrent illness – infective illnesses such as pyelonephritis, appendicitis, pneumonia
  • Cervical weakness
  • Idiopathic

Risk factors

  • Previous preterm births
  • Multiple pregnancy
  • Cervical damage
  • Fibroids
  • Factors in current pregnancy
    • Recent antepartum haemorrhage
    • Intercurrent illness
    • Surgery
  • Parity (0 or >5)
  • Ethnicity – black women
  • Poor socio-economic status
  • Smoking
  • Drugs of abuse especially cocaine
  • Low body weight
  • Inter-pregnancy interval of less that 1 year

Investigations

  • Bedside fibronectin
  • Cervical length measured by transvaginal ultrasound. A normal cervix measures around 35mm
  • Repeat vaginal examination

Preterm pre-labour rupture of membranes (PPROM)

  • Hx reporting ‘gush of fluid’ vaginally – must be distinguished from leaking urine
  • Following rupture of membranes fetal movements will be reduced in strength/frequency
  • Diagnosis can only be made following a speculum examination revealing a pool of fluid in the posterior vagina
  • Vaginal examination should be avoided

Investigations

  • Nitrazine testing – tests pH. Amniotic fluid is alkaline and vaginal secretions are acidic
  • Genital tract swabs – helps guide antibiotic therapy
  • Maternal well being – temp, BP, pulse
  • Fetal well being – serial antepartum cardiotocography
  • Ultrasound – amniotic fluid vol
  • Amniocentesis – gram stain, microscopy, culture

Treatment

  • Maternal steroids – reduces neonatal RDS
  • Tocolytics – e.g. ritodrine is a beta2 agonist. Atosiban is an oxytocin antagonist, indomethacine. Can delay delivery giving time for steroid treatment and organisation of neonatal care
  • Antibiotics – particularly after PPROM
  • Caesarean section – at early gestation and oligohydramnios, lower uterine segment is often poorly formed. Riskier vertical uterine incisions are often required

Management of high-risk asymptomatic women

  • Early dating scan
  • Treatment of bacterial vaginosis
  • Treatment of bacteruria
  • Prophylaxis against Group B strep
  • Cervical ultrasound to assess cervical length
  • Fetal fibronectin testing – can only be undertaken after 23 weeks. High levels may be physiological before then

Malpresentation and Malposition

Breech presentation

  • Presentation of the buttocks occurs in 3% of term pregnancies but is more common in early pregnancy and can complicate preterm deliveries
  • Extended breech – both legs extended at the knee
  • Flexed breech – both legs flexed at the knee
  • Footing breech – one of both feet present below the buttocks

Aetiology

  • No cause
  • Prematurity
  • Conditions that prevent fetal movement – e.g. twin pregnancy
  • Conditions that prevent engagement of the head – placenta praevia, pelvic tumours, pelvic deformities

Complications

  • Increase in perinatal and long term morbidity and mortality
  • Higher incidence of neurological handicap
  • Increase risk of cord prolapse
  • Trapping of head upon delivery
  • Cessation of progress of labour

Management

  • External cephalic version (ECV)
    • Attempted after 37 weeks
    • Under ultrasound guidance
    • Risk of placental abruption and uterine rupture
  • Caesarean section – safer than vaginal delivery

  • Vaginal breech birth
    • More risky for large fetus or if there is evidence of fetal compromise
    • Important than fetal neck is flexed
    • Can result in slow dilatation and poor decent in second stage. Pushing is not advised until buttocks are visible
    • Requires an episiotomy after then buttocks distend the perineum
    • The fetus is as far as the umbilicus without traction
    • The legs can be flexed out of the vagina whilst the back is kept anterior
    • When the scapula is visible the arms can be hooked down by sweeping a finger over the shoulder and across the chest
    • Once the back of the neck is visible, the legs are held up whilst forceps are applied
    • With the next contraction the head is lifted slowly out of the vagina

Abnormal lie (transverse and oblique)

  • Lie of the fetus defines the relationship of the fetus with the long axis of the uterus
  • Occurs in 1 in 200 births but in more common earlier in pregnancy

Aetiology

  • Preterm labour
  • Conditions which allow more room to turn – polydramnios, lax uterus following multiparity
  • Conditions which prevent turning –twin pregnancy
  • Conditions which prevent engagement – placental praevia, pelvic tumours, uterine abnormalities

Complications

  • Obstruction leading to uterine rupture

Management

  • Caesarean section

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Disclaimer: These notes are my own personal study aid - DO NOT use them for medical advice!