Non-infectious genital lumps/ulceration
Vulval papillomatosis
- Lesions resemble condyloma (genital wart) but most are HPV negative
- At the central margin of the vestibule frond-like projections may be seen
- May be normal anatomical variant
- Soft, whereas warts are hard
Fibroepithelial polyps
- Also know as skin tags or acrochordon
- Small, soft, common, benign, usually pedunculated neoplasm
- More common in the obese
Fordyce’s spots
Small, painless, raised white spots on the shaft of the penis or labia
Form of ectopic sebaceous gland
Behcets disease
- Recurrent multifocal disorder
- Immune medicated, associated in particular with HLA-B51
- Most common onset in the thirties
- Male predominance
- Racial predilection for individual from the middle east and japan
- Diagnostic criteria
- Recurrent oral ulcers – minor/major aphthous ulcers and herpetiform ulcers
- Recurrent genital ulceration – major/minor aphthous ulcers and herpetiform ulcers, occurs mostly in females. Can result in dysuria or dyspareunia
- Eye lesions – uveitis, vasculitis
- Skin lesions – pustular lesions, erythema nodosum
- Recurrent oral ulcers – minor/major aphthous ulcers and herpetiform ulcers
- Additional features
- Neurological features – brain stem syndromes, spinal cord involvement, meningomyelitis, meningoencephalitis
- Arthritis/ arthralgia
- Vascular lesions – thrombophlebitis of leg veins, ascribed to decreased plasma fibrinolytic activity
- Neurological features – brain stem syndromes, spinal cord involvement, meningomyelitis, meningoencephalitis
Aphthous Ulcers
- Also called canker ulcers
- Ulceration of the mucosal epithelium
- Appears to be immune mediated – T cells
- Minor aphthous ulcers are yellow/grey ulcers, less than 10mm in diameter erythematous surround. Tend to heal without scarring after 7-10 days
- Major aphthous ulceration are greater than 10mm in diameter and are very painful and frequently scar