Non-infectious genital lumps/ulceration

Vulval papillomatosis

  • Lesions resemble condyloma (genital wart) but most are HPV negative
  • At the central margin of the vestibule frond-like projections may be seen
  • May be normal anatomical variant
  • Soft, whereas warts are hard

 

Fibroepithelial polyps

  • Also know as skin tags or acrochordon
  • Small, soft, common, benign, usually pedunculated neoplasm
  • More common in the obese

 

Fordyce’s spots

Small, painless, raised white spots on the shaft of the penis or labia

Form of ectopic sebaceous gland

 

 

Behcets disease

 

  • Recurrent multifocal disorder
  • Immune medicated, associated in particular with HLA-B51
  • Most common onset in the thirties
  • Male predominance
  • Racial predilection for individual from the middle east and japan
  • Diagnostic criteria
    • Recurrent oral ulcers – minor/major aphthous ulcers and herpetiform ulcers
    • Recurrent genital ulceration – major/minor aphthous ulcers and herpetiform ulcers, occurs mostly in females. Can result in dysuria or dyspareunia
    • Eye lesions – uveitis, vasculitis
    • Skin lesions – pustular lesions, erythema nodosum
  • Additional features
    • Neurological features – brain stem syndromes, spinal cord involvement, meningomyelitis, meningoencephalitis
    • Arthritis/ arthralgia
    • Vascular lesions – thrombophlebitis of leg veins, ascribed to decreased plasma fibrinolytic activity

 

Aphthous Ulcers

 

  • Also called canker ulcers
  • Ulceration of the mucosal epithelium
  • Appears to be immune mediated – T cells
  • Minor aphthous ulcers are yellow/grey ulcers, less than 10mm in diameter erythematous surround. Tend to heal without scarring after 7-10 days
  • Major aphthous ulceration are greater than 10mm in diameter and are very painful and frequently scar

 

Leave a Reply



Disclaimer: These notes are my own personal study aid - DO NOT use them for medical advice!