Pelvic inflammatory disease (PID)

  • Characterised by;
    • Pelvic pain
    • Adnexal tenderness
    • Fever
    • Vaginal discharge

 

  • Results from infection by either;
    • Gonococcus
    • Chlamydiae
    • Enteric bacteria
  • In the case if spontaneous/induced abortions and delivery can also be caused by;
    • Staphylococci
    • Streptococci
    • Coliform bacteria
    • Clostridium perfrigens
    • These tend to spread up the genital tract by the vasculature rather than the mucosa

 

  • Once gonococcus is with the fallopian tubes acute suppurative salpingitis develops
  • The tubal serosa becomes hyperaemic and layered with fibrin
  • The lumen fills with purulent exudates that may leak out via the fimbrial end
  • In days or weeks the fimbria may seal against the ovary to create salpingo-oophoritis
  • Collections of pus within the ovary and tube (tubo-ovarian abscess) or tubal lumen (pyoslapinx) may occur
  • Adhesions of the tubal plica ,may produce glandlike structures (follicular salpingitis)
  • In the course of time, the pus may breakdown to a thin serous fluid to form a hydrosalpinx
  • PID caused by strep, straph and the other puerperal organisms produce less exudation within the tube lumen with less involvement of the mucosa and more inflammation in the deep layers
  • The infection tends to spread throughout the wall to involve the serosa, broad ligament, pelvic structures and peritoneum
  • Staph and strep infections are more likely to cause a bacteraemia

 

  • Complications of PID
    • Peritonitis
    • Intestinal obstruction due to adhesions
    • Bacteraemia (may produce endocarditis, meningitis, suppurative arthritis)
    • Infertility

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Disclaimer: These notes are my own personal study aid - DO NOT use them for medical advice!